Mitochondrial Oxidative Phosphorylation: Nuclear-Encoded Genes, Enzyme Regulation, and Pathophysiology (Advances in Experimental Medicine and Biology, 748)
Product Description
Mitochondrial Oxidative Phosphorylation: Nuclear-Encoded Genes, Enzyme Regulation, and Pathophysiology (Advances in Experimental Medicine and Biology, 748)
This book will describe the nuclear encoded genes and their expressed proteins of mitochondrial oxidative phosphorylation. Most of these genes occur in eukaryotic cells, but not in bacteria or archaea. The main function of mitochondria, the synthesis of ATP, is performed at subunits of proton pumps (complexes I, III, IV and V), which are encoded on mitochondrial DNA. The nuclear encoded subunits have mostly a regulatory function. However, the specific physiological functions of the nuclear encoded subunits of complexes I, III, IV, and V are mostly unknown. New data indicates that they are essential for life of higher organisms, which is characterized by an adult life without cell division (postmeiotic stage) in most tissues, after the juvenile growth. For complex IV (cytochrome c oxidase) some of these subunits occur in tissue-specific (subunits IV, VIa, VIb, VIIa, VIII), developmental-specific (subunits IV, VIa, and VIIa) as well as species-specific isoforms. Defective genes of some subunits were shown to induce mitochondrial diseases. Mitochondrial genes and human diseases will also be covered.
Technical Specifications
You might also like
ELCOKITEX 2Pcs Car Female Cigarette Lighter Adapter Add-a-Circuit TAP Adapter Extension 11.8 Inch Cable with 12V 24V Fuse Holder for Low Profile Mini (LP Mini) APS ATT Blade Fuses CFH-TAPLPMI-10ADY
ELCOKITEX 8Pcs 12V Add-a-Circuit Mini Fuse Tap APM ATM Blade Fuse Holder Automotive Replacement Holder Adapter Simple Safety Device for DIY/Car/Truck/Boat/RV/SUV CFH-TAPMI-5AJY
ELCOKITEX 2Pcs Car Female Cigarette Lighter Adapter Add-a-Circuit TAP Adapter Extension 11.8 Inch Cable with 12V 24V Fuse Holder for Micro 2 (M2) APT ATR Blade Fuses CFH-TAPM2-10ADY
ELCOKITEX 2Pcs Inline Fuse Holder Maxi APX Add-a-Circuit Car Fuse Holder TAP Adapter 70A Blade Automotive Fuse Holder for Automotive Marine CFH-ILMAXI-PT70A
ELCOKITEX 4Pcs Auto Blade Standard ATC ATO Fuse Holder Seat 32V Panel Mount Blade Fuse Block for Car Van Motorcycle Motorhome Scooter Quad Boat Marine Tractor Solar Project CFH-PCBATO-KCD3
ELCOKITEX 2Pcs Car Female Cigarette Lighter Adapter Add-a-Circuit TAP Adapter Extension 11.8 Inch Cable with 12V 24V Fuse Holder for Mini APM ATM Blade Fuses CFH-TAPMI-10ADY
ELCOKITEX 15Pcs Auto Blade Standard ATC ATO Fuse Holder Seat with Cover Black for Car Boat Truck SUV CFH-PCBATO-EDZ
ELCOKITEX 6Pcs 30A Add-a-Circuit Low Profile Mini Fuse Tap Automotive Replacement APS ATT Blade Fuse Holder 12V Fuse Adapter Jumper Connector for Car/Truck/Boat/RV/SUV CFH-TAPLPMI-30AL